86 of the Best Midwestern Casseroles

Updated: May 10, 2024

These are our very best casseroles from the midwest. Even the contributors say so!

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Church Supper Hot Dish

This recipe was in my mother’s church cookbook, and now it’s in my church cookbook! Apparently is was too good to miss a generation. I often make this dish to take along to potlucks…and it seems that if I don’t, someone else will! It’s hearty and so tasty! —Norma Turner, Haslett, Michigan

Go To Recipe

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Artichoke & Spinach Chicken Casserole

Try this homey and comforting casserole for an alternate main dish at Thanksgiving. The spinach adds nice color, and the red pepper flakes add a pleasant, mild heat. —Janice Christofferson, Eagle River, Wisconsin
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Chile Tamale Pie

This crowd-pleasing potluck dish packs a little heat, a little sweet and a big-time authentic southwestern flavor. There is no substitute for freshly ground chiles. A small food processor on high speed may be used to grind the chiles and cumin, or use a dedicated coffee grinder for fresh spices. It’s a terrific $15 investment for fresh spices anytime—and your palate will thank you! —Ralph Stamm, Dayton, Ohio
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Sausage and Rice Casserole Side Dish

When company's coming or when I need a quick-and-easy dish to pass, this is my hands-down favorite. A neighbor introduced me to the delicious combination of fluffy rice and sage-seasoned sausage. One forkful was all it took to convince me that I'd found a winner. —Joyce Green, Bettendorf, Iowa
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Spaghetti Squash Casserole Bake

One of our daughters shared this recipe along with squash from her first garden.—Glenafa Vrchota, Mason City, Iowa
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Chicken and Wild Rice Bake

My chicken and rice bake is a lovely example of midwestern cuisine. The dish is ideal for hosting parties because it can bake while you turn your attention to other preparations. —Suzanne Greenslit, Merrifield, Minnesota
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Cheesy Pizza Casserole

I discovered this recipe in the reader's exchange page of our local electric cooperative's magazine. Serve it whenever you've got a crowd to please!—Judy Chandler, Franklin, Kentucky
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Fold-Over Tortilla Bake

Here’s something a little different to shake up taco night. But don’t reserve this zippy dish for a weeknight—it’s perfect for potlucks and serving company, too. something a little different from the usual tacos. It's special enough for potlucks or dinner guests. —Deborah Smith, DeWitt, Nebraska
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Chicken Casserole

The original old family recipe for this chicken casserole called for the sauce to be made from scratch. Through the years, I developed this version that takes less time to prepare and still tastes great. It's an attractive main dish. —Ruth Van Dyke, Traverse City, Michigan
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Enchilada Casserole

Every time I serve this dish, I get satisfied reviews—even from my father, who usually doesn't like Mexican food. Plus, it smells delicious while baking. —Nancy VanderVeer, Knoxville, Iowa
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Eggsquisite Breakfast Casserole

I developed this recipe over 20 years ago. The rich warm sauce tastes especially great on cold winter mornings. I hope your family enjoys it as much as mine! — Bee Fischer, Jefferson, Wisconsin
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Taco Cornbread Casserole

A whole can of chiles adds fire to this casserole. For less heat, you can use just enough of the can for your taste. —Lisa A. Paul, Terre Haute, Indiana
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Winter Squash Casserole

Years ago, our vegetable garden kept us well-supplied all year long. Dad stored huge piles of potatoes and squash in the coldest part of the basement. In winter the squash was so hard. Mother sometimes used an ax to cut it into small pieces for cooking! Her hard work was worth it, because we really enjoyed this wonderful casserole! —Glendora Hauger, Siren, Wisconsin
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Chicken & Dumpling Casserole

This classic, savory casserole is one of my husband's favorites. He loves the fluffy dumplings with plenty of gravy. The basil adds just the right flavor and makes the whole house smell so good while this dish bakes. —Sue Mackey, Jackson, Wisconsin
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Pork and Green Chile Casserole

I work at a local hospital and another job part time, so I'm always on the lookout for good, quick recipes to fix for my family. Some of my co-workers and I exchange recipes. This zippy casserole is one that was brought to a picnic at my house. People raved over it. —Dianne Esposite, New Middletown, Ohio
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Creamy Noodle Casserole

My husband, Ronald, works long hours and frequently doesn't arrive home until past 7 p.m. This casserole is ideal for those late nights—it's just as tasty after it's been warmed in the microwave. —Barb Marshall, Pickerington, Ohio
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Beef 'n' Biscuit Bake

This recipe is quick, easy and satisfying. With its beef and corn combo, it's cozy cuisine at its best! —Erin Schneider, St. Peters, Missouri
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Ham and Swiss Casserole

When I prepare this noodle casserole for church gatherings, it's always a hit. It can easily be doubled or tripled for a crowd. —Doris Barb, El Dorado, Kansas
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Fiesta Chicken

Chili powder and picante sauce add just the right dash to this hearty main dish. It's a snap to assemble since it uses convenience foods. —Teresa Peterson, Kasson, Minnesota
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Cheeseburger French Fry Casserole

Kids love this cheeseburger french fry casserole because it combines two of their favorite fast foods. And I like the fact that I can whip it up with just four ingredients. —Karen Owen, Rising Sun, Indiana
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Potluck Taco Casserole

This is the dish I most often take to potlucks, and the pan comes home empty every time. —Kim Stoller, Smithville, Ohio
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Cauliflower Casserole

To dress up cauliflower, Mom used a delightful mixture of a cheesy sauce, bright red and green pepper pieces and crushed cornflakes. Leftovers were rare. —Linda McGinty, Parma, Ohio
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Church Supper Spaghetti

Because this recipe feeds so many, I often take it to church dinners and potlucks. This colorful dish also comes in handy when we have lots of help to feed on our farm. —Verlyn Wilson, Wilkinson, Indiana
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Burrito Bake

Back when I was in college, my roommate would frequently make this economical baked burrito casserole. It's so easy to put together, and one serving goes a long way. —Cindee Ness, Horace, North Dakota
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Slow-Cooked Enchilada Casserole

Tortilla chips and a side salad turn this savory casserole into a fun and festive meal with very little effort. —Denise Waller, Omaha, Nebraska
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Twice-Baked Potato Casserole

My daughter gave me this recipe because she knows I love potatoes. The hearty casserole is loaded with a palate-pleasing combination of bacon, cheeses, green onions and sour cream. —Betty Miars, Anna, Ohio
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Sloppy Joe Under a Bun

I usually keep a can of sloppy joe sauce in the pantry, because our kids love sloppy joes. But sometimes I don't have buns on hand. With this fun casserole, we can still enjoy the flavors that they love in a flash. The bun-like top crust is made with biscuit mix, sprinkled with sesame seeds and baked until golden. —Trish Bloom, Ray, Michigan
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Firecracker Casserole

My husband and I love this southwestern-style firecracker casserole. The flavor reminds us of enchiladas, but the recipe doesn't require the extra time to roll them up. —Teressa Eastman, El Dorado, Kansas
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French Toast Casserole

Topped with cinnamon and sugar, this overnight French toast casserole is my favorite way to make this breakfast favorite. Since you assemble this baked French toast the night before, you save time in the morning, and if you have an extra hungry crowd, it's easy to bake up a few batches. —Sharyn Adams, Crawfordsville, Indiana
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Chicken Noodle Casserole

Everyone who tries this comforting cheesy chicken casserole asks for the recipe. It's so simple to make that sometimes I feel as if I'm cheating! —Kay Pederson, Yellville, Arkansas
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Taco Salad Casserole

This taco casserole recipe tastes like a taco salad and is a breeze to assemble. I crush tortilla chips to form a bottom layer, then spread on refried beans, a spicy meat mixture and cheese. —Rhonda McKee, Greensburg, Kansas
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Cashew Chicken Casserole

I especially like this dish because I can get it ready the day before I need it. It's easy to whip up with common pantry items, including macaroni, canned soup and saltine crackers. —Julie Ridlon, Solway, Minnesota
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Cheesy Beef Casserole

This hearty casserole tastes like lasagna and makes a satisfying meal when served with a green salad and garlic bread. —Ardyce Piehl, Poynette, Wisconsin
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Nacho Chicken

I have been serving this rich and zippy chicken casserole for years, and it's a favorite of my family and friends. It disappears quickly at bring-a-dish gatherings, too. —Thom Britton, Three Rivers, Michigan
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Chili Mac Casserole

This cheesy casserole uses several of my family's favorite ingredients, including macaroni, kidney beans, tomatoes and cheese. Just add a leafy salad for a complete meal. —Marlene Wilson, Rolla, North Dakota
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Tortilla Pie

My husband and I enjoy this southwestern take on lasagna because it’s not as dense or heavy as traditional layered dishes made with pasta. Our two daughters enjoy the mild flavor. —Lisa King, Caledonia, Michigan
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Amish Breakfast Casserole

We enjoyed hearty breakfast casseroles during a visit to an Amish inn. When I asked for a recipe, one of the women told me the ingredients right off the top of her head. I modified it a bit to create this version that my family loves. —Beth Notaro, Kokomo, Indiana
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Tuna Noodle Casserole

Families are sure to love the creamy texture and comforting taste of this traditional tuna casserole that goes together in a jiffy. I serve it with a green salad and warm rolls for a nutritious supper. —Ruby Wells, Cynthiana, Kentucky
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Baked Chops and Cottage Fries

Convenience items like frozen vegetables, cottage fries and a jar of cheese sauce make it a snap to assemble this comforting pork chop supper. It's a simple one-dish meal. —Gregg Voss, Emerson, Nebraska
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Cornbread Taco Bake

Cornbread and beef bake together in one casserole dish, making this entree convenient. This Mexican cornbread casserole is packed with tempting seasonings, and the cheese and onions make an attractive topping. —Vicki Good, Oscoda, Michigan
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Chicken and Swiss Stuffing Bake

I love to cook but just don't have much time. This casserole is both comforting and fast, which makes it my favorite kind of recipe. I serve it with a green salad. —Jena Coffey, Sunset Hills, Missouri
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Artichoke Egg Casserole

This is a great recipe for a brunch. I serve it with fresh stir-fried asparagus, a fruit salad and croissants. —Marilyn Moores, Indianapolis, Indiana
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Taco Noodle Dish

I got creative while we were housebound during a snowstorm one winter...and used ingredients I had on hand to come up with this hearty casserole. Later, I modified it so it has less fat and fewer calories. —Judy Munger, Warren, Minnesota
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Chicken Zucchini Casserole

A co-worker shared this chicken zucchini casserole recipe that was originally her grandmother's. When I make it, I use precooked chicken from the grocery store and fresh zucchini my neighbor gives me from his garden. —Bev Dutro, Dayton, Ohio
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Creamy Turkey Casserole

I sometimes make turkey just so I have the extras for this casserole! —Mary Jo O'Brien, Hastings, Minnesota
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Angel Hair Shrimp Bake

Shrimp pairs beautifully with the herbs, salsa and three kinds of cheese in this baked angel hair pasta casserole. The shrimp make this dish special enough for a guests, but your family is sure to enjoy it, too. —Susan Davidson, Elm Grove, Wisconsin
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Mexicali Casserole

If you like Mexican food but are watching your diet, try this tasty bake. It takes advantage of ground turkey and reduced-fat cheese without sacrificing flavor. —Gertrudis C. Miller, Evansville, Indiana
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Cheesy Hamburger Supper

I have good memories of eating this all-in-one meal often while growing up. We all loved the flavor and seldom had leftovers. Instead of sprinkling it with cheddar, I sometimes create a cheese sauce using American cheese and milk. It makes it so cheesy! —Andrea Brandt, Newton, Kansas
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Biscuit Turkey Bake

As a college student, I go for stick-to-your-ribs foods that are also easy on the budget. Here's one that fits the bill. I like to bake this casserole for friends' birthdays. —Stephanie Denning, Mt. Pleasant, Iowa
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Seafood Casserole

A family favorite, this rice casserole is filled with plenty of seafood and veggies. It's hearty, homey and so easy to make. —Nancy Billups, Princeton, Iowa
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Mexican Turkey Skillet

This family-friendly main dish with turkey, black beans and vegetables has a rich Mexican flavor that may seem indulgent, but it’s delightfully light. Created by our Test Kitchen, it cooks in one skillet, so it’s a snap to clean up for a weeknight supper.
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Spicy Nacho Bake

I made this hearty, layered southwestern casserole for a dinner meeting once, and now I'm asked to bring it every time we have a potluck. Everybody loves the beefy bean filling and crunchy, cheesy topping. —Anita Wilson, Mansfield, Ohio
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Loaded Red Potato Casserole

This potato casserole has the same flavor of the potato skins you can order as a restaurant appetizer. It's an ideal dish for tailgating and potlucks. —Charlane Gathy, Lexington, Kentucky
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Pizza Noodle Bake

Here’s a family-pleasing casserole that comes together in a snap, making it perfect for a weeknight meal. Double the recipe and freeze one for later! —Bernice Knutson, Soldier, Iowa
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Chicken Tater Bake

You'll please everyone in the family with this inviting and filling chicken Tater Tot casserole. It tastes like a chicken potpie topped with Tater Tots. —Fran Allen, St Louis, Missouri
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Meaty Pasta Casseroles

I love this recipe because it makes two hearty casseroles. Every time I make it I add a little something different, such as extra garlic, to give it an added boost of flavor. —Debra Butcher, Decatur, Indiana
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Crescent Turkey Casserole

How do you make a dinner of turkey and vegetables appealing to kids? You turn it into a pie, of course! My version tastes classic but doesn’t take any time at all. —Daniela Essman, Perham, Minnesota
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Makeover Tater-Topped Casserole

I love Tater Tot casserole, but wanted a lighter version of the recipe. The Taste of Home Test Kitchen slashed the fat in this classic dish, while keeping all the Tots my family loves. Who know you could have healthy Tater Tots?! —Scott Woodward, Shullsburg, Wisconsin
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Beef & Tater Bake

The entire family will enjoy this heartwarming, all-in-one dinner. Plus, it offers easy cleanup! —Mike Tchou, Pepper Pike, Ohio
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Ham & Spinach Casserole

This is down-home cooking at its best! Ham and veggies join forces with a creamy sauce and pretty topping to create a hearty one-dish meal. —Taste of Home Test Kitchen
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Slow-Cooked Stuffed Peppers

My favorite kitchen appliance is the slow cooker, and I use mine more than anyone else I know. It does a great job with this good-for-you dish. —Michelle Gurnsey, Lincoln, Nebraska
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Roast Beef with Chive Roasted Potatoes

It’s hard to believe that last night’s beef roast could get any better, but it shines in this heartwarming dish. —Taste of Home Test Kitchen
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Sweet Potato Enchilada Stack

These sweet potato stacks have a spicy kick the whole family will love. Mexican flavors abound in this awesome enchilada stack jampacked with black beans and sweet potato. —Taste of Home Test Kitchen
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Chicken & Cheese Noodle Bake

This is the recipe my daughters and I often make for new parents when they come home from the hospital. With its creamy spaghetti filling and melted cheese topping, this casserole holds a nice cut and comforts hungry tummies. —Fancheon Resler, Bluffton, Indiana
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Salsa Verde Chicken Casserole

This is a rich and surprisingly tasty rendition of a number of Tex-Mex dishes fused into one packed, beautiful casserole. Best of all, it’s ready in hardly any time! —Janet McCormick, Proctorville, Ohio
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Broccoli Tuna Casserole

When I was in the Navy, a co-worker's wife shared this recipe with me. I’ve tweaked it over the years, but it still brings back memories of my family away from home. —Yvonne Cook, Haskins, Ohio
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Chicken & Egg Noodle Casserole

A friend and her family went through a really difficult time, and I felt so awful for them. Bringing over this chicken noodle casserole was the one thing I could think of to help them out in a tiny way and let them know I was thinking of them. —Lin Krankel, Oxford, Michigan
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Tex-Mex Summer Squash Casserole

Mild-flavored yellow squash gets a big boost from flavor-packed chiles, jalapenos and red onion. This side dish also works with zucchini. —Tommy Lombardo, Euclid, Ohio
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Deluxe Hash Brown Casserole

My son-in-law gave me the recipe for this hash brown casserole, which my kids say is addictive. It's an amazing make-ahead dish.—Amy Oswalt, Burr, Nebraska
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Hash Brown & Chicken Brunch Casserole

My husband and I love to have a hot breakfast, but find it difficult with two kids. This dish is excellent to prepare the night before and bake the next day for your family or to take into work to share with co-workers—there are never any leftovers.—Jennifer Berry, Lexington, Ohio
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Grilled Cheese & Tomato Soup Bake

This casserole brings together two classic comfort foods: grilled cheese sandwiches and tomato soup. There’s no need for your hands to get messy dipping bread into a bowl of hot soup! Best of all, my picky-eater husband devours every bite. —Megan Kuns, Perrysburg, Ohio

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Chicken Chiles Rellenos Casserole

My husband likes Mexican food and casseroles, so I combined the two. This chicken with poblanos and chiles satisfies our craving for dinner at a Mexican restaurant. —Erica Ingram, Lakewood, Ohio
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Chicken & Cheddar Biscuit Casserole

I always get rave reviews when I bring this casserole to my son's Cub Scout meetings.This is the perfect comfort meal after a long day. —Sarah Phillips, East Lansing, Michigan
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Ham & Veggie Casserole

I’ve paired ham with broccoli and cauliflower for years. To complete this casserole dinner, I pass around some dinner rolls. —Sherri Melotik, Oak Creek, Wisconsin
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Bacon Cheeseburger Tater Tot Bake

This bacon cheeseburger tater tot casserole is the perfect dish to bribe your kids; homework, chores, piano practice—consider them done! —Deanna Zewen, Union Grove, Wisconsin
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Chicken Tamale Bake

When I serve this Mexican-style casserole, everyone scrapes the plate clean. Offer fresh toppings like green onions, tomatoes and avocado. —Jennifer Stowell, Smithville, Missouri
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Mushroom Penne Bake

This is an easy, hearty and delicious meal for a chilly evening! Its cheesy goodness will have you going in for seconds. Serve with salad and garlic bread. —Sue Aschemeier, Defiance, Ohio
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Oven-Baked Shrimp & Grits

On chilly days, I doctor up grits and top them with shrimp for a comfy meal. If you’re not a seafood lover, use chicken, ham or both. —Jerri Gradert, Lincoln, Nebraska
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Broccoli-Cauliflower Chicken Casserole

A chicken, broccoli and rice casserole is one of our favorite comfort foods. I make my easy variation in the slow cooker. You can easily substitute whatever cheese you prefer. I sometimes use dairy-free cheese to create a more paleo-friendly dinner. The dish is also delicious sprinkled with a simple bread crumb topping. —Courtney Stultz, Weir, Kansas
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Deluxe Pizza Casserole

This is the family favorite dish for special occasions, and we always make it for my granddaughter's birthday. Mushrooms are a wonderful addition if you like them. —Vickie Oldham, Dubuque, Iowa
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Chicken & Swiss Casserole

It's nice to have an alternative to the traditional baked ham on Easter. This comforting casserole is always a crowd-pleaser. Using rotisserie chicken from the deli makes prep simple. —Christina Petri, Alexandria, Minnesota
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Pizza Lover's Casserole

When you're looking for a surefire crowd-pleaser for a kids' party, it's hard to go wrong with pizza. This dish delivers the taste of pizza in a convenient and delicious casserole. Pair it with a salad and bread, and you have a great meal for a table full of kids without the pizzeria tab! —Jackie Hannahs, Cedar Springs, Michigan
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Spaghetti Squash Meatball Casserole

One of our favorite comfort-food dinners is spaghetti and meatballs. We're crazy about this lighter, healthier version that features so many veggies. It has the same beloved flavors with more nutritious ingredients! —Courtney Stultz, Weir, Kansas
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Thai Peanut Chicken Casserole

I used traditional pizza sauce and toppings in this recipe for years. After becoming a fan of Thai peanut chicken pizza, I decided to use those flavors instead. Serve this dish with stir-fried vegetables or a salad with sesame dressing for an easy, delicious meal. —Katherine Wollgast, Troy, Missouri
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Bacon Breakfast Casserole

This easy breakfast dish allows me to make a comforting family favorite that doesn't take a lot of prep. It's also great for big brunch gatherings. —Paula Lawson, Springfield, Ohio