Layered Deli Loaf

Total Time

Prep: 15 min. + chilling


8 servings

Updated: Oct. 04, 2022
This recipe is special to me because it was handed down from my grandma. A tangy sauce, flavored with horseradish and Dijon mustard, sparks a hearty assortment of meats and cheeses. It feeds a crowd, so it's perfect for a party or a potluck. My husband says it's the best sub sandwich he's ever had. -Sarah Kraemer, Rockford, Illinois


  • 1/4 cup mayonnaise
  • 2 tablespoons prepared horseradish, drained
  • 1 tablespoon Dijon mustard
  • 1 round loaf (1 pound) unsliced bread
  • 2 tablespoons butter, softened
  • 1/3 pound thinly sliced deli ham
  • 1/3 pound sliced Monterey Jack cheese
  • 1/3 pound thinly sliced deli turkey
  • 1/3 pound sliced cheddar cheese
  • 1/3 pound thinly sliced deli roast beef
  • 1 medium tomato, sliced
  • 1 large dill pickle, sliced lengthwise
  • 1 small red onion, thinly sliced
  • Lettuce leaves


  1. In a small bowl, combine the mayonnaise, horseradish and mustard. Cut bread in half. Carefully hollow out bottom and top of loaf, leaving 3/4-in. shell (discard removed bread or save for another use). Spread butter on cut sides of bread.
  2. In the shell, layer ham, a third of the mayonnaise mixture, Monterey Jack cheese, turkey, a third of the mayonnaise mixture, cheddar cheese, roast beef, remaining mayonnaise mixture, tomato, pickle, onion and lettuce.
  3. Replace top. Wrap tightly in plastic wrap; cover and refrigerate for at least 1 hour.

Nutrition Facts

1 piece: 474 calories, 25g fat (12g saturated fat), 75mg cholesterol, 1541mg sodium, 33g carbohydrate (3g sugars, 2g fiber), 27g protein.