Mexican Chicken Alfredo Recipe
Mexican Chicken Alfredo Recipe photo by Taste of Home

Mexican Chicken Alfredo Recipe

Publisher Photo
One family member likes Italian; another likes Mexican. They’ll never compromise when this is on the menu. —Tia Woodley, Stockbridge, Georgia
TOTAL TIME: Prep: 25 min. Bake: 30 min.
MAKES:8 servings
TOTAL TIME: Prep: 25 min. Bake: 30 min.
MAKES: 8 servings


  • 1 package (16 ounces) gemelli or spiral pasta
  • 2 pounds boneless skinless chicken breasts, cubed
  • 1 medium onion, chopped
  • 1/4 teaspoon salt
  • 1/4 teaspoon pepper
  • 1 tablespoon canola oil
  • 2 jars (15 ounces each) Alfredo sauce
  • 1 cup grated Parmesan cheese
  • 1 cup medium salsa
  • 1/4 cup 2% milk
  • 2 teaspoons taco seasoning

Nutritional Facts

1-1/2 cups equals 559 calories, 20 g fat (11 g saturated fat), 102 mg cholesterol, 899 mg sodium, 55 g carbohydrate, 3 g fiber, 40 g protein.


  1. Preheat oven to 350°. Cook pasta according to package directions.
  2. Meanwhile, in a large skillet over medium heat, cook chicken, onion, salt and pepper in oil until chicken is no longer pink. Stir in Alfredo sauce; bring to a boil. Stir in cheese, salsa, milk and taco seasoning.
  3. Drain pasta; toss with chicken mixture. Divide between two greased 8-in.-square baking dishes. Cover and bake 30-35 minutes or until bubbly. Yield: 2 casseroles (4 servings each).
Originally published as Mexican Chicken Alfredo in Simple & Delicious August/September 2011, p22

Nutritional Facts

1-1/2 cups equals 559 calories, 20 g fat (11 g saturated fat), 102 mg cholesterol, 899 mg sodium, 55 g carbohydrate, 3 g fiber, 40 g protein.

This recipe pairs well with a full-bodied white wine.

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Reviewed Sep. 25, 2014

We really liked this dish! I have a friend who thinks everything is hot including salsa so we put sour cream on top and she even thought it was delicious! I was out of milk so I used buttermilk.

Reviewed Sep. 17, 2014

This recipe is a new favorite in our house. I agree with other reviewers and will increase the amount of taco seasoning next time but it was still delicious.

Reviewed Sep. 3, 2014

I made this dish for my family and everyone loved it! Now, it is a favorite of my sisters and she makes it for her friends and family. I made it exactly as stated. Makes yummy leftovers for lunch the next day!

Reviewed Sep. 3, 2014

Oh so good! I made 1/2 a recipe and changed 2 things...I used leftover chicken (worked very nice) and a 1/2 package of taco seasoning. I will make this again.

Reviewed Aug. 18, 2014

I really wanted to like this. Love pasta, love Mexican & love alfredo. Only changes made were, based on other reviews, added whole pkg. of taco seasoning & a 7 oz. can of green chilies. Sorry, but just tasted like a glorified mac & cheese.

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