Mexican Ground Beef Casserole

Total Time

Prep: 20 min. Bake: 40 min.


6 servings

Updated: Oct. 15, 2023
Born out of a need to rid the fridge of extras, this Mexican ground beef casserole recipe is flexible. Add more corn to make it sweeter, if you like. You can also spice it up as hot or mild as you want. —David Mills, Indianapolis, Indiana
Mexican Ground Beef Casserole Recipe photo by Taste of Home


  • 1-1/2 pounds ground beef
  • 1 envelope taco seasoning
  • 3/4 cup water
  • 1 can (16 ounces) refried beans
  • 1/2 cup salsa
  • 6 flour tortillas (6 inches)
  • 2 cups frozen corn, thawed
  • 2 cups shredded cheddar cheese
  • Optional: Shredded lettuce, chopped tomatoes, sliced ripe olives and sour cream


  1. Preheat oven to 350°. In a large skillet, cook beef over medium heat until no longer pink; drain. Stir in taco seasoning and water. Bring to a boil. Reduce heat; simmer, uncovered, 5 minutes.
  2. Meanwhile, in a microwave-safe bowl, combine beans and salsa. Cover and microwave 1-2 minutes or until spreadable.
  3. Place 3 tortillas in a greased round 2-1/2-qt. baking dish. Layer with half the beef, bean mixture, corn and cheese; repeat layers.
  4. Bake, uncovered, until cheese is melted, 40-45 minutes. Let stand 5 minutes. If desired, serve with lettuce, tomatoes, olives and sour cream.

Mexican Ground Beef Casserole Tips

How should you store Mexican ground beef casserole?

Like other casserole recipes, you can store this ground beef casserole in an airtight container for up to three to four days. Here's how long other leftovers last.

How can you make this Mexican ground beef casserole gluten-free?

To make this casserole gluten-free, make sure to choose a gluten-free tortilla and taco seasoning (yes, gluten can sneak into taco seasoning!). Here are some of our other favorite gluten-free Mexican recipes.

How can you make this Mexican ground beef casserole vegetarian?

Swap the ground beef for a meat substitute, like black beans, to make a vegetarian casserole.

Christina Herbst, Taste of Home Assistant Digital Editor

Nutrition Facts

1-1/4 cups: 602 calories, 31g fat (14g saturated fat), 107mg cholesterol, 1404mg sodium, 43g carbohydrate (3g sugars, 5g fiber), 36g protein.