Cook pasta according to package directions. Meanwhile, in a Dutch oven, cook beef over medium heat until no longer pink; drain. Stir in spaghetti sauce and salsa. Drain pasta; stir into meat mixture.
Transfer to a greased 13x9-in. baking dish (dish will be full). Cover and bake at 350° for 40 minutes. Uncover; sprinkle with cheese. Bake 8-12 minutes longer or until heated through and cheese is melted.