In a small bowl, combine lime juice and honey. Pour 1/2 cup into a large resealable plastic bag; add the fish. Seal bag and turn to coat; refrigerate for up to 1 hour. Place remaining mixture in a small saucepan; set aside.
Drain fish and discard marinade. Sprinkle fillets with chili powder; place on a greased broiler pan.
Broil 4-6 in. from the heat for 12-15 minutes or until fish flakes easily with a fork. Meanwhile, bring reserved lime juice mixture to a boil. Reduce heat; simmer, uncovered, until reduced by half. Spoon over fillets.