What is the difference between white wine vinegar and distilled white vinegar? Can they be used interchangeably? —E.K., Roseville, CaliforniaDistilled white vinegar is made from a grain alcohol mix. It has a strong sharp flavor and is most often used for pickling foods and as a cleaning agent. White wine vinegar is made from white wine and, although its flavor is pungent, it is milder than distilled white vinegar. For savory dishes, most people prefer white wine vinegar.