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Mexican Chicken Alfredo Recipe

Mexican Chicken Alfredo Recipe

One family member likes Italian; another likes Mexican. They’ll never compromise when this is on the menu. —Tia Woodley, Stockbridge, Georgia
TOTAL TIME: Prep: 25 min. Bake: 30 min. YIELD:8 servings


  • 1 package (16 ounces) gemelli or spiral pasta
  • 2 pounds boneless skinless chicken breasts, cubed
  • 1 medium onion, chopped
  • 1/4 teaspoon salt
  • 1/4 teaspoon pepper
  • 1 tablespoon canola oil
  • 2 jars (15 ounces each) Alfredo sauce
  • 1 cup grated Parmesan cheese
  • 1 cup medium salsa
  • 1/4 cup 2% milk
  • 2 teaspoons taco seasoning


  • 1. Preheat oven to 350°. Cook pasta according to package directions.
  • 2. Meanwhile, in a large skillet over medium heat, cook chicken, onion, salt and pepper in oil until chicken is no longer pink. Stir in Alfredo sauce; bring to a boil. Stir in cheese, salsa, milk and taco seasoning.
  • 3. Drain pasta; toss with chicken mixture. Divide between two greased 8-in. square baking dishes. Cover and bake 30-35 minutes or until bubbly.
    Freeze option: Cover and freeze unbaked casserole up to 3 months. To use, thaw in refrigerator overnight. Remove from refrigerator 30 minutes before baking. Preheat oven to 350°. Bake casserole, covered, 50-60 minutes or until bubbly. Yield: 2 casseroles (4 servings each).

Nutritional Facts

1-1/2 cup: 559 calories, 20g fat (11g saturated fat), 102mg cholesterol, 899mg sodium, 55g carbohydrate (4g sugars, 3g fiber), 40g protein .

Reviews for Mexican Chicken Alfredo

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HaleysFunFixins 245818
Reviewed Mar. 22, 2016

"Delicious... I made it once as is with chicken and it was great, but the second time around I substituted turkey kielbasa for the chicken and it made the dish even better! The key is using a salsa that you really like."

caree929 245784
Reviewed Mar. 21, 2016

"Per other reviews, I didn't use as much onion and added a full packet of taco seasoning, but this was really good! It had lots of flavor and just the right amount of spice."

Jacklyn0810 239356
Reviewed Dec. 13, 2015

"It's a fine recipe. My family just didn't love it."

myweisenberger 233576
Reviewed Sep. 27, 2015

"Love it Kids said its a "Do Again!""

jstowellsupermom 225172
Reviewed Apr. 20, 2015

"Great recipe! I was out of salsa so I used green enchilada sauce instead and I used a whole packet of taco seasoning. Whole family loved it!!"

Jenna092 215649
Reviewed Dec. 22, 2014

"When I first came across this recipe, I thought that the fusion of chicken Alfredo and Mexican was a bit strange, but it looked so good! I loved how it was creamy, but still had some kick to it. I added green chilies and loved them in there. Now my apartment smells like my dinner!"

momio 132196
Reviewed Sep. 25, 2014

"We really liked this dish! I have a friend who thinks everything is hot including salsa so we put sour cream on top and she even thought it was delicious! I was out of milk so I used buttermilk."

momof2inpa 196323
Reviewed Sep. 17, 2014

"This recipe is a new favorite in our house. I agree with other reviewers and will increase the amount of taco seasoning next time but it was still delicious."

bjpalmer 178189
Reviewed Sep. 3, 2014

"I made this dish for my family and everyone loved it! Now, it is a favorite of my sisters and she makes it for her friends and family. I made it exactly as stated. Makes yummy leftovers for lunch the next day!"

ColleenaG 193382
Reviewed Sep. 3, 2014

"Oh so good! I made 1/2 a recipe and changed 2 things...I used leftover chicken (worked very nice) and a 1/2 package of taco seasoning. I will make this again."

Fllutterbye 150347
Reviewed Aug. 18, 2014

"I really wanted to like this. Love pasta, love Mexican & love alfredo. Only changes made were, based on other reviews, added whole pkg. of taco seasoning & a 7 oz. can of green chilies. Sorry, but just tasted like a glorified mac & cheese."

judontmesswithme 196322
Reviewed Aug. 12, 2014

"I would give it 4-1/2 if I could. This was a very tasty dish. My family enjoyed it. It's VERY filling, and it made great leftovers for the next day's lunch."

Relayer 123736
Reviewed Aug. 12, 2014

"Love this dish! Make it all the time and love that I can make one and put one in the freezer for later. I boil my chicken ahead of time and debone and then make the rest of recipe."

luigimon 111649
Reviewed Apr. 5, 2014

"This is sooooooooooo good!!!! Going in my Favorites!"

karrisadyan 111648
Reviewed Mar. 6, 2014

"This was a tasty meal. The alfredo with the taco seasoning was a very interesting combo."

schapdel 191956
Reviewed Feb. 10, 2014

"Very tasty although I didn't use all the onion and added a little more grated Parmesan. Mild enough for those like myself who enjoy the spicy flavor without the burn. Would probably be good with shredded chicken, green onion, and maybe some mozzarella and sour cream."

mbclumsy 117211
Reviewed Jan. 27, 2014

"This turned out WAY too oniony. Just not good."

brettacuff 133009
Reviewed Jan. 4, 2014

"Needs more taco seasoning than the recipe calls for originally. Had extremely high hopes for this dish and was somewhat disappointed with the outcome. It actually tasted better the day after, reheated in the microwave."

crazylegs53 123734
Reviewed Sep. 25, 2013

"This recipe is wonderful. I read the reviews beforehand and therefore used fajita seasoning in place of the taco seasoning which gave it a little more kick, I also added more Parmesan cheese and used natural cut salsa in place of regular salsa. It was awesome and will make it again. It is a lot like a dish that Red Robin used to serve."

TiKiTango 132195
Reviewed Aug. 4, 2013

"Oh my goodness this is so delish! The first time I made it as written, except I made my own alfredo. The second time I added a little more salsa and taco seasoning. SO GOOD!!! Couldn't find gemelli, but had cavatappi on hand. It soaked up too much sauce for me, the next time I used mini bow ties. It was easier to eat for my 1 and 3 year old."

4Huskers 111646
Reviewed Feb. 20, 2013

"I made this today and it was absolutely wonderful!!! I only made half the recipe since there is only 2 of us and it was perfect. Like others, I added more taco seasoning and put some cheese on top for the last 5 minutes. I was super good!!"

Czwhiz 132192
Reviewed Jan. 5, 2013

"Everyone loved it! Next time I'm going to try medium salsa verde. I have hungry teenage boys so I doubled the recipe and made 2 9x12s and a small casserole for 2 for my mom. Thanks for the recipe."

horsey_mom 196168
Reviewed Oct. 27, 2012

"Even my pickiest eater loved this! I will be making this again!"

naydan 179245
Reviewed Oct. 11, 2012

"This pasta dish is so creamy and flavorful! My husband loved it!"

KimmyGTx0312 212523
Reviewed Oct. 1, 2012

"I saw this version in the Taste of Home Freezer Meal small little cookbook at a local store...Intrigued as I love both Mexican and Italian as well, I tried it and froze it!!! Oh My Goodness!! DELICIOUS!! I will definatley be making it again!!! Sooooooo Wonderful and full of flavor!!"

qgal 184515
Reviewed Sep. 11, 2012

"unbelievably delicious!!! never a left over with this recipe :)"

trivershill 212522
Reviewed Sep. 5, 2012

"Delicious recipe! I prepared salad to eat with this dish to make it a healthier meal."

qgal 123733
Reviewed Aug. 19, 2012

"More than 5 stars ! With my 2 Autistic, very Picky eaters, this recipe help up beautifully !!! We all loved it and it will be a family favorite for years to come. Tomorrow at work, I will share this recipe with the whole company :)"

BLmomma217 195010
Reviewed Aug. 14, 2012

"I added a little extra cumin and chili powder along with an entire packet of taco seasoning. I also added a can of rotel because I didn't have much salsa. My oven is broke so I couldn't bake it with cheddar cheese on top like I wanted to, so I stirred a little in.

My boyfriend and I enjoyed this, but I'm not 100% sure I will make this again."

Spiritthing69 196167
Reviewed Jul. 22, 2012

"In order to make it a little healthier I made my own Alfredo sauce, the sauce in the jars is so awful for you. It was amazing. I will make it again and again."

lisettejohns 117344
Reviewed Jul. 17, 2012

"I love getting recipes like this - they are easy, the kids will eat them and they taste great!

I also added extra taco seasoning and left the additional milk out because I didn't think it needed it."

glrbsn 117209
Reviewed Jul. 11, 2012

"My family thought this was great and ask for it again and again. Very good."

szahradnik 150267
Reviewed Jul. 11, 2012

"My family enjoyed this. My sons went back for seconds. I doubled the taco seasoning as we like things spicy. I will make this again."

elynoon 184511
Reviewed Apr. 10, 2012

"First recipe in a long time that made the entire family happy - even picky teenagers. We make this by demand atleast once a month. The only change I make is, I add cheese on top as well and bake last 5 minutes or so without foil to seal the top of the dish. We also do not split the recipe. This is enough for a huge Pyrex dish and it is gone by the next day. Very tasty!"

lisareiger 179244
Reviewed Apr. 2, 2012

"Made this for my very picky mother(haha) and she loved it! Everyone in my family did. Actually making dinner for my mother again for her birthday and she asked me to make this again. Very easy to make and delicious!!"

msymonds 193381
Reviewed Feb. 23, 2012

"I made this for dinner one out and it was wonderful! when my parents came to visit i told them about it and they said i had to make it again! I made it for them last night and it was a HUGE hit! I even had to give the recipe to my mom to make it home! Great dish!"

lilysille 193379
Reviewed Jan. 31, 2012

"Unfortunately I couldn't put salsa and onion in it cuz then my boys wouldn't eat it so I just use onion powder and extra taco seasoning, maybe half of a package. Everyone loves it. You know its good when the hubby tells you 3 times throughout the night. Making it again tonight but I only have half a jar of alfredo so I'll add a bit of homemade. YUM!"

manuahs 117207
Reviewed Jan. 26, 2012

"This was fabulous! I love that I ususally have all of this in the pantry at all times. This is a quick, great tasting meal."

amandavaldez 193378
Reviewed Jan. 21, 2012

"Everyone LOVED this recipe. I had 2 families and ours over last night and served all of it. I tweaked it a little. I put in a whole green pepper. A half of a red onion. Added a can of diced green chilies. I used leftover roasted chicken and a whole packet of taco seasoning.

Will definitely make this again!"

looking4recipes 117343
Reviewed Jan. 16, 2012

"I noticed in the reviews how some people liked it if they omitted something or added something. So I only used one box of noodles, 2 lbs of chicken, 1 jar of alfredo, 3/4 cup parmesan, 1/4 milk, 2 tsp os seasoning. It came out awesome. It wasn't even this mexican chicken alfredo because of all those changes but more of an amazing mac and cheese."

boodee95 184449
Reviewed Jan. 12, 2012

"i haven't made this yet, but was wondering if i added mexicorn to it, how that would taste? so at least there is some sort of veggie in there...aside from the salsa, of course..."

carollachman 196165
Reviewed Dec. 12, 2011

"Absolutely yummy!"

lisareiger 132188
Reviewed Nov. 22, 2011

"This recipe is wonderful. It is great for something different. However, I just noticed the recipe calls for 2 teaspoons of taco seasoning. I used 2 tablespoons (oops) it tasted wonderful like this though. Will definately make this again. And it was supper easy."

lawhopes 179241
Reviewed Nov. 20, 2011

"This is just wonderful. Great comfort food and not too hard to make. I use a chipotle salsa- gives it an extra kick."

emerald_Frog06 117334
Reviewed Oct. 23, 2011

"The picture isn't very descriptive of how the food actually looks when cooked. The salsa overpowered the entire dish. If I made it again, I would probably add more taco seasoning, no salsa, corn, bell peppers, and cheddar cheese on the top to make it a taste better. Was soarly dissapointed."

lydstew 133007
Reviewed Oct. 22, 2011

"I thought this was quite creamy and delicious, but it was a little heavy on spice for the kids. If I made it again, I would definitely use mild salsa, or even just diced tomatoes, but we're kind of wimps with heat. :)"

kagreenawalt 191907
Reviewed Oct. 20, 2011

"Loved this recipe, it was so yummy my 4 year old even liked it."

jstroudpainter16 117311
Reviewed Oct. 19, 2011

"I made it tonight for dinner and my picky eater liked it and even asked for more. My family had me make sure that I had the stuff to make more again. Great job!!"

bjsilve0 193375
Reviewed Oct. 19, 2011

"ICK!! Neither of us liked it."

NaisMommy 133005
Reviewed Sep. 13, 2011

"My daughter and boyfriend loved it!"

DarkestDay 191889
Reviewed Sep. 5, 2011

"Cut the recipe in half and added extra taco seasoning. Both my husband and I loved it!"

CLKneifel 195008
Reviewed Aug. 30, 2011

"I cut the recipe in half. It was wonderful! Next time I make it I will decrease the amount of pasta (so it is creamier) and increase the taco seasoning (it could be a little spicier). But, overall a great dish!"

melissa1sch 123732
Reviewed Aug. 21, 2011

"This was wonderful! Rarely do myself, my husband and son all love a recipe, but this one did it. Highly recommended."

coco1712 117308
Reviewed Aug. 10, 2011

"Loved, loved this!"

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Wine Pairings

Full-Bodied White Wine

Enjoy this recipe with a full-bodied white wine such as Chardonnay or Viognier.