Hearty Pepperoni Pizza Casserole Recipe
Hearty Pepperoni Pizza Casserole Recipe photo by Taste of Home
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Hearty Pepperoni Pizza Casserole Recipe

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4.5 26 37
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Friends and family love my new spin on pizza. Packed with cheeses, meats, and tomatoes, this hearty pasta dish will go fast! Nancy Foust Stoneboro, Pennsylvania
TOTAL TIME: Prep: 20 min. Bake: 30 min.
MAKES:16 servings
TOTAL TIME: Prep: 20 min. Bake: 30 min.
MAKES: 16 servings


  • 3 cups uncooked spiral pasta
  • 2 pounds ground beef
  • 1 medium onion, chopped
  • 2 cans (8 ounces each) mushroom stems and pieces, drained
  • 1 can (15 ounces) tomato sauce
  • 1 jar (14 ounces) pizza sauce
  • 1 can (6 ounces) tomato paste
  • 1/2 teaspoon sugar
  • 1/2 teaspoon garlic powder
  • 1/2 teaspoon onion powder
  • 1/2 teaspoon dried oregano
  • 4 cups (16 ounces) shredded part-skim mozzarella cheese, divided
  • 1 package (3-1/2 ounces) sliced pepperoni
  • 1/2 cup grated Parmesan cheese

Nutritional Facts

1 each: 296 calories, 14g fat (7g saturated fat), 51mg cholesterol, 616mg sodium, 19g carbohydrate (5g sugars, 2g fiber), 23g protein.


  1. Preheat oven to 350°. Cook pasta according to package directions.
  2. Meanwhile, in a Dutch oven, cook beef and onion over medium heat until meat is no longer pink; drain. Stir in mushrooms, tomato sauce, pizza sauce, tomato paste, sugar and seasonings. Drain pasta; stir into meat sauce.
  3. Divide half of the mixture between two greased 11x7-in. baking dishes; sprinkle each with 1 cup mozzarella cheese. Repeat layers. Top each with pepperoni and Parmesan cheese.
  4. Cover and bake 20 minutes. Uncover; bake 10-15 minutes longer or until heated through. Yield: 2 casseroles (8 servings each).
Originally published as Pizza Casserole in Taste of Home December/January 2007, p42

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styff2015 User ID: 8015909 237937
Reviewed Nov. 23, 2015

"OH my!!!! This is so yummy!"

nancymcf User ID: 5846378 160973
Reviewed Oct. 19, 2014

"Great recipe. My colleagues thought this was wonderful."

gertysgoods User ID: 7601727 160971
Reviewed Jan. 12, 2014

"My sons favorite!!! Check my blog out for more recipes"

HeidiX0X0 User ID: 7220638 166218
Reviewed Apr. 10, 2013

"M family loved this recipe! I added black olives and green pepper. This recipe could be made healthier by simply adjusting the ingredients (wheat pasta, ground turkey, low fat cheese etc.). The bad rating based on the saturated fat content is wrong. Plus Heidimotsch doesn't mention this is a recipe for 2 meals!"

lululove User ID: 7173538 73112
Reviewed Mar. 12, 2013


heidimotsch User ID: 6151061 89809
Reviewed Jan. 27, 2012

"This is a good example of why so many Americans are overweight - 2 pounds of ground beef, 4 1/2 cups of cheese AND a whole package of pepperoni? I could have poured the grease of the top there was so much. It would be pretty good if lightened up, but as is, too unhealthy and full of saturated fat."

lurky27 User ID: 1251896 166217
Reviewed Jan. 25, 2012

"I love recipes that easily make 2 batches. This is delicious and easy to bake. turkey pepperoni works great.

~ Theresa"

JFenrick User ID: 1441711 166215
Reviewed Jan. 8, 2012

"This was very easy and delicious. It does make a lot. I used extra hamburger...yummy!"

MommyofAndrewAddyAlex User ID: 6084994 73094
Reviewed Nov. 29, 2011

"Yummy!!!!! It is easy to make, and the whole family loves it :)"

TwylahJean User ID: 5706947 144228
Reviewed Sep. 10, 2011

"Hubby & I loved it, but it sure makes a lot! Like the idea of making up all the sauce & freezing half of it for the next time."

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