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Family-Favorite Meat Loaf Recipe

Family-Favorite Meat Loaf Recipe

Combining ground beef with ground turkey is the key to this flavorful meat loaf that's sure to become a menu staple. Horseradish adds just the right amount of zip. It has my husband's seal of approval! —Colette Gerow, Raytown, Missouri
TOTAL TIME: Prep: 15 min. Bake: 45 min. YIELD:6 servings


  • 1/3 cup egg substitute
  • 1 can (6 ounces) tomato paste, divided
  • 2 tablespoons Dijon mustard
  • 2 teaspoons prepared horseradish, divided
  • 1/2 cup quick-cooking oats
  • 1 envelope onion soup mix
  • 1-1/2 teaspoons garlic powder
  • 1 teaspoon steak seasoning
  • 1 pound lean ground beef
  • 1/2 pound lean ground turkey
  • 1 teaspoon water
  • 1/2 teaspoon sugar


  • 1. In a large bowl, combine the egg substitute, 1/2 cup tomato paste, mustard, 1 teaspoon horseradish, oats, soup mix, garlic powder and steak seasoning. Crumble beef and turkey over mixture and mix well.
  • 2. Shape into a loaf and place in an 11-in. x 7-in. baking dish coated with cooking spray. Combine the water, sugar, remaining tomato paste and remaining horseradish; spread over meat loaf.
  • 3. Bake, uncovered, at 350° for 45-55 minutes or until a meat thermometer reads 165°. Drain if necessary. Yield: 6 servings.

Nutritional Facts

1 slice: 250 calories, 10g fat (3g saturated fat), 76mg cholesterol, 763mg sodium, 16g carbohydrate (5g sugars, 3g fiber), 24g protein. Diabetic Exchanges: 3 lean meat, 1 vegetable, 1 fat, 1/2 starch.

Reviews for Family-Favorite Meat Loaf

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BIGRUNNINGTAZ User ID: 94457 110272
Reviewed Jan. 19, 2013

"This is really good and even better as leftovers."

Karnold249 User ID: 4181483 177150
Reviewed Jan. 12, 2013

"I followe the recipe exactly and it was terrific. When I told my husband it was good enough for company, he replied he didn't want to share it with company."

OhBarbi User ID: 5434643 177149
Reviewed Jan. 8, 2013

"Very tasty, made according to recipe. I would have liked a little more sauce on top and also some chopped green pepper in the mix, but it has a good flavor."

jillanglemyer User ID: 2065875 142845
Reviewed Jan. 7, 2013

"@ Dave I have never seen a " sick" meat loaf. I think the word would be "healthful". This is very good meat loaf."

Dave Janis User ID: 5847151 110271
Reviewed Jan. 6, 2013

"Meatloaf is supposed to be tasty...not healthy."

cafeheaven2 User ID: 4340441 160070
Reviewed Jan. 6, 2013

"Wow! For flavor and texture it'd be hard to beat this recipe. If you have a yearning for Meat Loaf, searching recipes and looking for "The One", then look no further. Making this one my "go to" meatloaf recipte."

PieGuy User ID: 1264421 110270
Reviewed Jan. 6, 2013


One large egg will be okay.
I used 2 with no problem."

DCHeilman User ID: 6136732 94215
Reviewed Jan. 6, 2013

"According to Egg Beater's web site, 3 tablespoons of egg substitue = one egg- there are 5.3 tablespoons in a 1/3 cup so if you use two eggs that should work.(it'd be a smidge more, but I don't think it should alter the recipe too much)"

cee-jay User ID: 1579946 160069
Reviewed Jan. 6, 2013

"Question: How many large eggs are equal to 1/3 cup egg substitute? I have the turkey and beef need to prepare this recipe but need to know how many eggs to use ASAP."

fredaevans User ID: 6360805 210382
Reviewed Jan. 6, 2013

"Not a Horseradish fan so I pass on that but do substitute red pepper flakes. Gives it a nice kick."

lurky27 User ID: 1251896 109768
Reviewed Mar. 16, 2011

"Yum! What a great combination of beef & turkey. We'll be making this again!

~ Theresa"

Grandmaj2u User ID: 189795 109767
Reviewed Feb. 25, 2009

"Very good! I did reduce the horseradish a bit as it is a bit too much for me. I also skip the onion soup and replace it with 1 t of onion powder and 1/2 an onion chopped up and 1 t worceshire sauce. This reduced the sodium, by a fair amount and ups the fiber a tiny bit."

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Wine Pairings

Light-Bodied Red Wine

Enjoy this recipe with a light-bodied red wine such as Pinot Noir.