Back to Creamy Pepperoni Ziti

Print Options


Card Sizes

Creamy Pepperoni Ziti Recipe

Creamy Pepperoni Ziti Recipe

You can easily feed a crowd with this simple dish that's ready in about 40 minutes. Its comforting sauce will become a fast favorite at your next potluck or weeknight dinner. —Charlane Gathy, Lexington, Kentucky
TOTAL TIME: Prep: 15 min. Bake: 25 min. YIELD:9 servings


  • 1 package (16 ounces) ziti or small tube pasta
  • 1 can (10-3/4 ounces) condensed cream of mushroom soup, undiluted
  • 3/4 cup shredded part-skim mozzarella cheese
  • 3/4 cup chopped pepperoni
  • 1/2 cup each chopped onion, mushrooms, green pepper and tomato
  • 1/2 cup half-and-half cream
  • 1/4 cup chicken broth
  • 1/4 teaspoon salt
  • 1/4 teaspoon garlic powder
  • 1/4 teaspoon pepper
  • 1/2 cup grated Parmesan cheese


  • 1. Cook pasta according to package directions; drain. In a large bowl, combine the pasta, soup, mozzarella cheese, pepperoni, onion, mushrooms, green pepper, tomato, cream, broth and seasonings.
  • 2. Transfer to a greased 13-in. x 9-in. baking dish. Sprinkle with Parmesan cheese. Cover and bake at 350° for 20 minutes. Uncover; bake 5-10 minutes longer or until bubbly. Yield: 9 servings.

Nutritional Facts

1 cup: 340 calories, 12g fat (6g saturated fat), 27mg cholesterol, 696mg sodium, 43g carbohydrate (4g sugars, 2g fiber), 15g protein Diabetic Exchanges: 3 starch, 1 high-fat meat, 0 fat.

Reviews for Creamy Pepperoni Ziti

Sort By :
ChocolateMudCake 153730
Reviewed Oct. 13, 2013

"This tastes delicious! My family requests it often. Thank You for sharing!"

msu4two 169792
Reviewed Sep. 22, 2013

"I made this tonight, and really liked it! I sauteed the vegetables prior to mixing them with the pasta mixture, and added 1/2 cup of chicken broth instead of 1/4 cup, as it seemed a bit dry. Although I like pepperoni, there was a bit too much for my taste, so I'll probably only use about 1/3 cup next time. I'll definitely make this again."

jmketchum1 153729
Reviewed Aug. 12, 2013

"Everyone loved it! Will make again"

blessedhomemaker 72509
Reviewed Aug. 29, 2012

"Fantastic! I agree with Jennifer that it tasted just like pizza toppings.I used penne pasta,cream instead of 1/2 and 1/2(the measurement called for plus a couple extra splashes),only half cut the pepperoni slices, and added 3/4C. more mozzarella cheese.We will have this again!"

deannasnz 80476
Reviewed May. 30, 2012

"I thought it was boring. Adding chicken and vegetables to the leftovers improved it."

MelodyMahala 99518
Reviewed Sep. 27, 2011

"I used the mini ziti pasta shells, the mini pepperoni slices and half a jar of sliced mushrooms instead of fresh. I also used fat free half-and-half and added another cup of shredded mozzarella on top of the casserole mixed with the parmesan cheese. It was perfect!"

Peaches_77 80462
Reviewed Aug. 29, 2011

"Really good, but I plan to change a couple of things the next time - it just says "chopped pepperoni" - I chopped it too small - think it would be better with bigger chunks. Also swap out the green peppers with roasted red peppers & will maybe add some chicken for a little extra substance."

brittanyminikus 209181
Reviewed Feb. 28, 2011

"Amazing! My husband couldn't stop complimenting the dish. I did add more cream of mushroom soup, more pepperoni, and sauted the veggies."

LaFrenierM 209180
Reviewed Feb. 19, 2011

"Saute the mushrooms, green peppers, onions, & add another can of cream of mushroom soup!!! :) A keeper! We enjoyed it much better the second time around when I made these changes!"

Flenner 80461
Reviewed Feb. 18, 2011

"This was sooo good. I added extra soup and a handful more pepperoni and cheese"

jshreckengast 156169
Reviewed Jan. 18, 2011

"So good. Will definitely keep this in the regular rotation."

ape360 169652
Reviewed Jan. 4, 2011

"sometimes less is more... i leave out the mushrooms,green pepper, and onion and it still tastes great! . LOVE IT"

JenniferMarie412 153727
Reviewed Jun. 19, 2010

"This pasta was GREAT! My boyfriend loved it too... it tastes like a supreme pizza... SO good and definitely a keeper! Also nice for days you forget to thaw out meat (which is why I made it!)"

ZTRAK 167388
Reviewed Jan. 16, 2010

"We love this flavorful recipe and I make it often. I prefer using less pasta (1/2 pkg.) which makes the finished casserole more moist."

sarahsomerlot 156168
Reviewed Mar. 5, 2009

"I thought this recipe was wonderful. With a tossed salad and some garlic bread, my family loved it!"

cntbailey 98040
Reviewed Feb. 4, 2009

"This was good but next time I make it I will add another can of cream of Mushroom soup. I little dry but will make this again."

scrambledwithcheese 98039
Reviewed Dec. 15, 2008

"Awful, just awful. Hated it."

hhe 169649
Reviewed Nov. 16, 2008

"Loved this recipe, my husband really enjoyed it aswell. It was simple, tasty, and really hearty. Definatly emailing it to all my friends"

bowler_jen 153725
Reviewed Oct. 31, 2008

"didn't like the un-sauteed onions, but the flavor in this is amazing and very quick to prepare. Will make again!"

aKelsey 156167
Reviewed Oct. 1, 2008

"Easier to prepare than falling off a log and just as affordable...which is good, because my husband couldn't stop eating it!"

eveann78 72508
Reviewed Sep. 26, 2008

"Wow this dish was amazing! Very easy to prepare. I actually used turkey pepperoni and frozen chopped stir fry mix so I didnt even have to cut up any peppers or onions. I didnt have mushrooms but it was fabulous without them. Im so glad there are leftovers!!"

Loading Image

Wine Pairings

Full-Bodied White Wine

Enjoy this recipe with a full-bodied white wine such as Chardonnay or Viognier.