Cajun Chicken Fettuccine Recipe
Cajun Chicken Fettuccine Recipe photo by Taste of Home

Cajun Chicken Fettuccine Recipe

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I combined two pasta sauces and added Cajun seasoning for kick in this quick- mix casserole. Using frozen onions and peppers speeds things up even more. Or try adding mushrooms or frozen peas. —Rebecca Reece, Henderson, Nevada
TOTAL TIME: Prep: 25 min. Bake: 25 min.
MAKES:8 servings
TOTAL TIME: Prep: 25 min. Bake: 25 min.
MAKES: 8 servings


  • 8 ounces uncooked fettuccine
  • 1 large sweet onion, halved and sliced
  • 1 medium green pepper, cut into 1/4-inch strips
  • 1 medium sweet red pepper, cut into 1/4-inch strips
  • 2 tablespoons olive oil
  • 2 cups cubed cooked chicken
  • 4 teaspoons Cajun seasoning
  • 1 teaspoon minced garlic
  • 1 jar (15 ounces) Alfredo sauce
  • 1/2 cup spaghetti sauce
  • 2 cups (8 ounces) shredded part-skim mozzarella cheese
  • 1/2 cup grated Parmesan cheese

Nutritional Facts

1 cup: 401 calories, 19g fat (9g saturated fat), 69mg cholesterol, 898mg sodium, 30g carbohydrate (5g sugars, 3g fiber), 27g protein


  1. Cook fettuccine according to package directions. Meanwhile, in a large skillet, saute onion and peppers in oil until tender. Add the chicken, Cajun seasoning and garlic; heat through. Transfer to a large bowl. Drain fettuccine; add to chicken mixture. Stir in Alfredo and spaghetti sauces.
  2. Transfer to a greased 13-in. x 9-in. baking dish. Sprinkle with cheeses. Cover and bake at 375° for 15 minutes. Uncover; bake 10-15 minutes longer or until golden brown. Yield: 8 servings.
Originally published as Cajun Chicken Fettuccine in Simple & Delicious January/February 2009, p18

Full-Bodied White Wine

Enjoy this recipe with a full-bodied white wine such as Chardonnay or Viognier.

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Reviewed Mar. 7, 2016

"Very Good. I roasted bone-in chicken breasts to get the 2 cups cooked chicken."

Reviewed Nov. 7, 2015

"Awesome recipe! We really enjoyed the creamy tomato sauce with the "kick" of Cajun. I used whole what spaghetti instead. I also did not assemble it into a casserole; I served the delicious sauce over servings of pasta. Will definitely make this again."

Reviewed Nov. 2, 2015

"You had me at "Cajun." We love spicy, so this caught my eye right away. My husband and I loved the creaminess of the sauce paired with the Cajun spice. Winner, Winner."

Reviewed Aug. 11, 2015

"My husband loved it! and it was better than I thought since Cajun seasoning doesn't appeal to me."

Reviewed Feb. 28, 2015

"Delicious. Make again."

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