Buttermilk Meat Loaf Recipe
Buttermilk Meat Loaf Recipe photo by Taste of Home

Buttermilk Meat Loaf Recipe

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Barbecue sauce is a Southwestern staple, so I use it in meat loaf instead of ketchup. The buttermilk and garlic also lend a tangy flavor. Whenever I serve this, it gets rave reviews, even from those who don’t ordinarily care for meat loaf.
TOTAL TIME: Prep: 20 min. Bake: 1 hour + standing
MAKES:6 servings
TOTAL TIME: Prep: 20 min. Bake: 1 hour + standing
MAKES: 6 servings


  • 1 cup soft bread crumbs
  • 2 eggs, lightly beaten
  • 1/2 cup finely chopped red onion
  • 6 tablespoons barbecue sauce, divided
  • 1/4 cup buttermilk
  • 2 tablespoons minced fresh parsley
  • 1 teaspoon garlic salt
  • 1/4 teaspoon pepper
  • 1-1/2 pounds ground beef

Nutritional Facts

2 slice: 0 calories, 0g fat (0g saturated fat), 0mg cholesterol, 0mg sodium, 0g carbohydrate (0g sugars, 0g fiber), 0g protein


  1. In a large bowl, combine the bread crumbs, eggs, onion, 4 tablespoons barbecue sauce, buttermilk, parsley, garlic salt and pepper. Crumble beef over mixture and mix well. Shape into a loaf. Place in a greased 11-in. x 7-in. baking dish.
  2. Bake, uncovered, at 350° for 50 minutes. Spread with remaining barbecue sauce. Bake 10 minutes longer or until meat is no longer pink and a meat thermometer reads 160°. Drain; let stand for 10 minutes before slicing. Yield: 6 servings.
Originally published as Buttermilk Meat Loaf in Country Extra November 2005, p49

Light-Bodied Red Wine

Enjoy this recipe with a light-bodied red wine such as Pinot Noir.

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Reviewed Feb. 16, 2016


Reviewed Nov. 22, 2015

"Most delicious meatloaf I ever ate. I'm watching my salt intake, so had to use a sub. But will always use this recipe."

Reviewed Nov. 10, 2015

"This was surprisingly better than I expected. I used Sweet Baby Ray's BBQ sauce and 1/2 pouch of Onion Soup Mix instead of a chopped up onion. Now one of my favorites! Very good!! And very good the next day, sliced up in a hot sandwich with gravy and mashed potatoes!!"

Reviewed Aug. 19, 2015

"I made this recipe tonight. I actually only had a half pound of ground beef 93/7. I made muffin meatloaves with this recipe. I was able to get about 8 muffin sized mini meatloaves. I topped them off with wihpped mashed potatoes pipped using a start-tip. I made them into savory cupcakes and were adorable! The meatloaf recipe has a lot of flavor! I baked the mini loaves at 350 degrees for 25 minutes which might have been too long since the temp was at 190 degrees so maybe try 20 minutes."

Reviewed Mar. 4, 2015

"Great taste and flavor. I used Montreal steak sauce instead of barbecue sauce."

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