Read reviews (45)
Rate recipe
Creamy, flavorful and so easy to fix, this meal-in-one will wow family and friends. Get ready for recipe requests for this easy chicken casserole! —Laura Kayser, Ankeny, Iowa
Nutritional Facts 1-1/3 cups equals 612 calories, 30 g fat (13 g saturated fat), 111 mg cholesterol, 829 mg sodium, 41 g carbohydrate, 3 g fiber, 42 g protein.
Originally published as Pesto-Chicken Penne Casseroles in Simple & Delicious May 2010, p59
Full-Bodied White Wine
Enjoy this recipe with a full-bodied white wine such as Chardonnay or Viognier.
Browse slideshows featuring our best recipes, holiday ideas, easy how-tos, cooking tips, and more!
Get Recipes >
A collection of our favorite, highest-rated recipes—including the best dessert, dinner and holiday recipes.
Tell us what you think of this recipe. Did you modify it? Would you make it again? Rate it today! >
Rate and Review this Recipe
Reviewed on Aug. 31, 2011 by oliv2646
I made this dish for a group of 60, and I got rave reviews! It did require some time, and I had help, but I will definitely make this again for my family soon.
Reviewed on Aug. 09, 2011 by ABRFosterMom
While time consuming, this was so worth it. I used homemade Alfredo sauce and home made pesto. I made this just as stated, except I added maybe 1tsp or so of fresh ground black pepper. This is definitely a company-worthy dish. I so admire people who dream up recipes like this! This is outstanding!!!! WOW!!
Reviewed on Jul. 06, 2011 by megantaylor
very easy to make
Reviewed on Jun. 26, 2011 by ssmith604
This casserole is just as good from the freezer and is excellent for potlucks!
Reviewed on May. 30, 2011 by jessicadarracott
This recipe is perfect just the way it is, although my husband prefers it with more spinach added. A little extra cheese doesn't hurt either. We can't go more than 2 weeks without making this one! Totally addicting.
Reviewed on May. 01, 2011 by millsapm
Very good, the 2nd one may have even been better... guess the flavors had a chance to meld more? Anyhow, served to the fam while in-laws were visiting and got compliments from everyone!
Reviewed on Apr. 06, 2011 by lynnincanadian
This dish has affectionately became known as "that stuff". There are never any leftovers
Reviewed on Apr. 05, 2011 by Summerjean22
This was so amazing!! My husband and I think it tastes just like Macaroni Grill's penne Rustica! The only thing I did different is saute some fresh garlic in some olive oil and then mixed in the alfredo. Again AMAZING!!!
Reviewed on Mar. 23, 2011 by scrapo
Great. Although next time I think I would try to make my own pesto to use and alfredo sauce. I accidentally forgot to buy the tomatoes at the store so I just chopped up some fresh tomatoes & red pepper, roasted them in the oven and added them. I also used a rotiserre chix to save on time. Used a mix of whole wheat and white pasta.
Reviewed on Feb. 11, 2011 by jonesy85
This was amazing , everyone in the family loved it and I loved that it made extra to freeze..Will make it again..
Our 10 most popular recipes for the month delivered right to your inbox!
© Reiman Media Group, LLC., 2013